Surgical Oncology Clinics of North America
Volume 17, Issue 4, Pages 709-996 (October 2008)
Regional Chemotherapy for Cancer
Edited by H.J. Wanebo
The current issue highlights the experience and the potential value of regional therapy and addresses many of the challenges to cancer therapy. The field continues to evolve and there is definite room for continued innovation not only for tumor access for the anticancer drugs but also for techniques to modify the drug delivery to improve access to the tumor cells themselves, which are often protected by various mechanisms, such as peri-tumor edema, in addition to the unique drug-resistant mechanisms in the tumor cell. The role for coupling biologic agents with chemotherapy to facilitate cancer therapy is under active exploration as is therapy with other agents that are gene derived or genetically engineered to facilitate therapy. These efforts will provide grounding for future development. The current articles highlight many future possibilities and past successes and limitations and we look forward to the continued future development of regional therapy.
http://rapidshare.com/files/162622005/socna_oct08.rar
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