Thursday, June 26, 2008

Options in the Treatment of Head and Neck Cancer


Options in the Treatment of Head and Neck Cancer
Publisher:CMPMedica | English | ISBN: 9781891483417 | 137 pages | 2006 | PDF | 3 MB

Description: Chemotherapy, as part of a multi-disciplinary and multi-modality approach, has become the standard of care for the treatment of locally advanced squamous cell cancer of the head and neck. Until recently, chemotherapy has been delivered as either induction chemotherapy, also known as neoadjuvant therapy, or in combination with radiotherapy as chemoradiotherapy (CRT). Although induction chemotherapy with cisplatinum and 5-fluorouracil (PF) is effective in improving survival, patients treated with induction chemotherapy have a high rate of local-regional failure despite a reduced rate of distant failure. CRT has improved survival by reducing local-regional failure, with no improvement in control of distant disease.
To optimize therapy, sequential therapy approaches, combining induction chemotherapy, CRT, and surgery have been developed. In addition, recent advances in induction chemotherapy, namely the demonstration that a three drug induction chemotherapy regimen with docetaxel, cisplatinum, and 5-fluorouracil (TPF) is significantly more effective than PF, has increased interest and optimism regarding the potential gains of induction chemotherapy, as a sequential therapy approach. Preliminary data support the use of sequential therapy in patients with poor-prognosis head and neck, and a phase III trial with this schedule shows highly encouraging improvements in survival, lessened toxicity, and a significant advantage to TPF in this setting. The different treatment paradigms of sequential therapy and CRT are being compared in phase III studies. TPF has replaced PF as the standard for induction chemotherapy, and sequential therapy represents an acceptable standard of care for patients with curable, locally advanced head and neck cancer.
http://w17.easy-share.com/1700732154.html

Tuesday, June 10, 2008

sset,kerala

Express News Service

T�PURAM: Applications have been invited for the post-graduate super speciality courses for 2008 in Thiruvananthapuram, Kottayam and Kozhikode Medical Colleges.

The course for which applications have been invited are MCH Paediatric Surgery, MCH Plastic Surgery, MCH Geneto Urinary Surgery, MCH Thoracic Surgery, MCH Neuro Surgery, MCH Gastro-Enterology Surgery, DM Cardiology, DM Gastro-Enterology, DM Neurology and DM Nephrology.

The candidates seeking admission to these courses should apply in the prescribed format, which can be downloaded from the official website cee-kerala.org of the Commissioner for Entrance Examinations from May 18, along with a demand draft of Rs 1,500 drawn from any nationalised bank, in favour of Commissioner for Entrance Examinations payable at Thiruvananthapuram. Service quota candidates who apply for general quota also should submit a demand draft for Rs 3,000.

The applications should reach the office of the Commissioner for Entrance Examinations, Housing Board Buildings, Santhi Nagar, Thiruvananthapuram - 695001 on or before 5 p.m. on June 12.

Sunday, June 1, 2008

Eosinophilic and Autoimmune Gastrointestinal Disease


Eosinophilic and Autoimmune Gastrointestinal Disease (US$99)
Stationary Office | Pages: 240 | 2008-06-28 | ISBN: 1416058400 | 5 MB

Eosinophilic esophagitis (EE) is a clinicopathologic disease characterized by upper intestinal symptoms and the finding of more than 15 or 20 eosinophils in the esophageal epithelium; these findings are unresponsive to proton pump inhibitor treatment. EE is a common disease that affects both children and adults. Some of the many important topics covered include eosinophilic esophagitis in adults and children, celiac disease, autoimmune pancreatitis, autoimmune hepatitis, enteric autoantibodies and gut motility disorders, autoantibodies and inflammatory bowel disease.


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